Out of total cases of infertility amongst a couple, approximately 40% are attributed to male-related issues. One of the underlying causes behind male-infertility is problem related to the sperm like low sperm count, poor sperm quality or abnormal sperms.
In most of the cases, a conventional ICSI procedure is performed where an expert embryologist visually examines the sperms using a microscope with magnification up to 400x and selects the normal motile sperms. However, in cases where the sperm samples are extremely low or highly abnormal, the experts at Southend prescribe the selection of sperms through IMSI or Intracytoplasmic Morphological Sperm Injection, an improved variation of ICSI.
IMSI is a technique that uses a high-powered microscope with magnification up to 6,000x to examine the sperms. The magnified digitally enhanced images of the sperm allow the embryologist to detect any structural alterations and abnormality that are otherwise hard to locate with conventional methods. This helps in selection of the quality sperms with most normal morphology for fertilization.
Intracytoplasmic morphologically selected sperm injection (IMSI) is a technique used in IVF treatment to examine and select sperm using a high-magnification digital imaging microscope.
With the IMSI technique,Embryologist are able to assess the structure of the sperm and exclude the sperm with suspected abnormalities from being injected into the available eggs.
Recommend IMSI if:
The IMSI treatment refers to the procedure of the IVF treatment that is done to examine and select sperm using a high-magnification digital imaging microscope for microinjection into the egg. This procedure helps a fertility doctor to assess the sperm structure and exclude the sperm with suspected abnormalities from being injected into the available eggs in a better way.
IMSI may improve the chances of in vitro fertilization and can be used after several unsuccessful IVFs. It is a real-time method in which a sperm is selected before the microinjection takes place.
After analyzing the sperm under advanced microscopes, the biologists are able to see the internal morphology of sperm and discard the ones with abnormalities. This effective selection of sperm without morphological alterations is believed to increase the chances of successful implantation of the pre-embryo and decrease the likelihood of miscarriage.
This technique still requires more study to demonstrate its efficacy and validity in order to be used routinely in the assisted reproduction laboratory and to be recommended by sufficient scientific evidence.
IMSI treatment may improve the chances of fertilization in vitro and can be used if you have performed several unsuccessful In Vitro Fertilization attempts.