Intrauterine insemination (IUI) has become the first-line management in infertility. It is a simple technique that involves the deposition of a washed semen sample into the woman’s uterus around the time of ovulation. The rationale is to increase the density of both eggs and sperm near the site of fertilization. This increases the likelihood of pregnancy.
The man provides a semen sample on the morning of insemination. This sample is prepared and then inserted through the woman’s cervix and into the uterus. The procedure takes place in our clinic. It is relatively painless. The patient is kept in bed for some time.
IUI is a relatively simple, non-invasive, cheap & easily repeatable procedure. However, careful selection of the patient is important. There is good evidence in the literature in favor of IUI as a cost-effective treatment for unexplained and mild, moderate male factor subfertility. Although it may take relatively more treatment cycles to achieve pregnancy, there are considerable advantages to the patient in terms of risk/benefit ratio and financial cost as compared with other ARTs.
Complications of IUI can include
What next after IUI?
If no pregnancy is achieved after 3 IUI’s, our specialists may recommend more advanced reproductive therapies such as IVF.
The success of IUI:
Success with IUI depends on what’s causing infertility i.e. the woman’s age, and total sperm count. If the count is good and the woman’s fallopian tubes are healthy, conception rates for IUI and COH are approximately 15-20 percent per cycle.
The Insemination usually takes only a few minutes, but you may be on fertility drugs for about a week before you ovulate. It also depends on the cause of the fertility problem, one may have three or four IUI cycles before getting pregnant or trying another treatment, such as in-vitro fertilization (IVF).
Some doctors are now advising women in their late 30s and older to try IVF even sooner that can be either as a first-line treatment or after just one or two unsuccessful IUI cycles.
The success rates depend on a couple's fertility problem as well as age. Studies have found that for couples suffering from unexplained infertility, the pregnancy rate for each natural IUI cycle is about 4 to 5 percent, and when fertility drugs are used, the pregnancy rate is about 7 to 16 percent. There are no national statistics on live birth rates.